building circuits in living cells

Synthetic biology researchers have demonstrated a new method for digital information processing in living cells, analogous to the logic gates used in electric circuits. The circuits are the largest ever published to date in eurkaryotic cells and a key step in harnessing the potential of cells as living computers that can respond to disease, efficiently produce biofuels or develop plant-based chemicals.

Journal Reference: Miles W. Gander, Justin D. Vrana, William E. Voje, James M. Carothers, Eric Klavins. Digital logic circuits in yeast with CRISPR-dCas9 NOR gates. Nature Communications, 2017; 8: 15459 DOI: 10.1038/NCOMMS15459

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